1 Cold Rice, Hot Topic — Rethinking Evolution from the Margins
In May 2025, Nature reported on a study that many hailed as a “landmark” in evolutionary biology. Conducted over more than a decade, the research showed that rice plants exposed to cold conditions for several generations acquired a stable tolerance to freezing temperatures — without any detectable changes to their DNA sequence. The adaptive trait was passed on through changes in epigenetic markers: molecular tags that regulate how genes are expressed, without altering the genetic code itself.
The rice plants had, in effect, inherited a new capacity not by mutating, but by modulating the expression of what was already possible. What made headlines, however, was not just the discovery itself, but how it was framed. “The study adds to evidence challenging the dominance of ‘natural selection’ as the sole adaptive force in evolution,” Nature reported. To some, this seemed to suggest a quiet revolution: evolution without mutation, inheritance without genes, adaptation without Darwin.
But what, exactly, is being challenged here — and what is being misunderstood?
As with many scientific breakthroughs, this study’s significance lies not only in its results but in what it invites us to reconsider. Yet to ask what this discovery means is to enter a space where biology and philosophy converge. What kind of thing is an adaptation? Where does variation come from? Can evolution be understood not only as a process of random mutations filtered by environmental selection, but as something more relational — something in which organism and environment co-participate in the actualisation of traits?
This series takes the rice study as a departure point for rethinking some of our inherited assumptions about evolution. It does not seek to discard natural selection, but to contextualise it. Nor does it argue that epigenetics overturns Darwinian evolution, as some popular accounts might imply. Instead, we ask: what happens when we stop treating genes as the sole site of evolutionary change, and begin to see adaptation as an unfolding within relationships — between organism and environment, past and future, potential and instance?
The cold-tolerant rice study is striking, not because it contradicts evolutionary theory, but because it exposes the limitations of a still-dominant narrative in which adaptation is framed as the gradual selection of random genetic variants. That narrative, often identified with the “Modern Synthesis” of mid-20th century biology, has long struggled to accommodate the plasticity, responsiveness, and situatedness that living systems exhibit. Evolution, we’re learning, is not only about what survives — but about what emerges, and how.
In the posts to follow, we’ll explore how epigenetics reshapes our understanding of variation, inheritance, and selection. We’ll look at how evolutionary biology is already moving beyond the gene-centric paradigm, and how a relational ontology might help make sense of this transition. Most of all, we’ll try to ask what it means to think with evolution — not as spectators watching traits compete for survival, but as participants in the very processes that shape the unfolding of life.
If rice can learn to grow cold within a few seasons, perhaps it is time we warmed to a more dynamic, relational view of evolution.
2 What Is Epigenetic Inheritance — and What Is It Not?
If evolution is typically understood as the selection of genetic variation, then epigenetics has arrived as something of a conceptual disruptor. In recent years, it has become a buzzword not only in biology but in popular science, psychology, and even wellness culture. Amid this proliferation of meanings, it’s worth pausing to ask: what do we actually mean by epigenetic inheritance? And just as importantly: what don’t we mean?
The rice study that sparked this series showed that cold tolerance could be passed from one generation to the next without changes to the DNA sequence. Instead, what changed were epigenetic markers — molecular tags (such as methyl groups) that affect whether specific genes are expressed or silenced. Crucially, these tags were heritable: they persisted across generations even when the original environmental trigger (cold stress) was removed.
This kind of inheritance challenges the narrowest reading of the “central dogma” of molecular biology, which once held that information flows one way: from DNA to RNA to protein. It also complicates the standard evolutionary account in which new traits arise through random mutations that, if beneficial, are retained through natural selection.
But epigenetic inheritance is not magic, nor is it a wholesale rejection of evolutionary theory. Rather, it invites us to broaden our framework. The question is not whether genetic change matters — clearly, it does — but whether all meaningful biological variation must be genetic in origin.
Epigenetics opens a space for adaptive plasticity: the ability of organisms to modulate their gene expression in response to environmental cues, in ways that can be passed on to offspring. It reintroduces the environment not just as a selective filter acting on random variation, but as a participant in the actualisation of variation itself.
Yet here is where we must tread carefully. To say that epigenetic changes are inherited is not to say that the environment can programme an organism’s traits at will. Nor does it mean that we have discovered a neo-Lamarckian mechanism in which acquired characteristics are routinely passed on. Most epigenetic marks are not stably inherited; many are reset during gamete formation or early development. What makes the rice study exceptional is precisely the durability of the observed changes.
We should also resist the temptation to think of epigenetics as somehow more “intentional” than mutation — as if the environment were purposefully sculpting traits in response to need. Evolution remains an emergent process, not a directed one. What epigenetics shows us is not that organisms consciously adapt, but that the boundary between organism and environment is more porous, and more responsive, than a strictly gene-centred model allows.
In this light, epigenetics may be less a repudiation of Darwinian evolution than a refinement — a gesture toward a more relational account of variation and inheritance. It suggests that evolutionary novelty can arise not only through randomness filtered by selection, but through context-sensitive modulation of existing potential.
Where genetic inheritance assumes a largely stable archive of possibility, epigenetic inheritance shows us how that archive can be dynamically interpreted. It is not the script that changes, but the reading of it.
In the next post, we’ll explore this idea further by asking: What counts as variation? And how might our assumptions about randomness, causality, and novelty be shaped by the models we use?
For now, the takeaway is this: epigenetics doesn’t replace the genetic model — but it helps us reframe the story of evolution as a more entangled, co-emergent process. One in which life does not simply adapt to its conditions, but evolves with them.
3 What Counts as Variation? Rethinking Evolution’s Raw Material
In classical evolutionary theory, variation is the fuel of change. Mutations — random changes in DNA — introduce novel traits, and natural selection acts on these traits to shape populations over time. From this perspective, variation is a kind of background noise: unpredictable, unstructured, and external to the processes that filter it.
But what if variation is not just random input, but relational output? What if what counts as “variation” depends not simply on chance, but on the ongoing interaction between organism and environment — and on the frameworks through which we interpret that interaction?
Let’s return to the rice study. The researchers didn’t observe a new gene, a mutation, or even a hybrid genotype. Instead, they observed a change in gene expression patterns — a difference not in what was present, but in how it was activated. This shift produced a functional difference (cold tolerance), and that difference persisted across generations.
So is this “variation”? If we define variation as differences in DNA sequence, then no. But if we define it more broadly — as the emergence of new traits with potential adaptive consequences — then yes. And crucially, this broader view allows us to see variation as something that can be induced, not just stumbled upon.
This challenges the idea that variation must be random to be evolutionary. The randomness of mutation has long served as a conceptual buffer between evolution and teleology: if change is random, then it cannot be purposeful. But randomness is not the same as independence. A dice roll is random, but it presupposes a system of rules, constraints, and possible outcomes. Likewise, epigenetically induced variation is not directed, but it is structured — shaped by the relational dynamics between organism and environment.
From a relational perspective, then, variation is not a static property of an isolated genome. It is an emergent property of interaction — of the organism’s openness to contextual influence, and the environment’s capacity to actualise different potentials. This is not to say that all variation is environmentally induced, but that even so-called “random” variation is only meaningful in relation to a system that constrains and interprets it.
This insight matters because it reframes how we understand novelty in evolution. In a strictly gene-centric model, novelty is additive: new traits arise when genetic accidents build up over time. But in a relational model, novelty can also be combinatorial and contextual — arising from new patterns of activation, new environmental triggers, or new configurations of interaction.
In this view, the question “what counts as variation?” is no longer a simple matter of molecular bookkeeping. It is a matter of framework — of how we define change, where we locate agency, and what kinds of difference we are prepared to recognise.
The rice didn’t gain a new gene. But it did gain a new capacity — one that emerged through its history of interaction with a particular stress, and that became inheritable through epigenetic marking. That change is as real, and as evolutionarily relevant, as any nucleotide substitution.
In the next post, we’ll explore how this redefinition of variation affects our understanding of inheritance. If traits can be passed on without changes to DNA, what does it mean to say that something is “inherited”? And how stable must a trait be to count?
4 What Counts as Inheritance? Expanding the Evolutionary Ledger
Inheritance has traditionally meant one thing in evolutionary theory: the transmission of genetic information from parent to offspring. Encoded in DNA, this information is thought to specify the organism’s developmental programme, which unfolds (with some environmental modulation) to produce traits. The rest — epigenetics, physiology, behaviour, culture — is considered either background noise or downstream consequence.
But the rice study demands a reconsideration. Here we find cold tolerance passed from one generation to the next, not through mutation or recombination, but through changes to chemical tags on the genome. These changes alter gene expression and persist for multiple generations. The underlying DNA remains constant. And yet, something clearly has been inherited.
This phenomenon is not new. In recent decades, biologists have documented epigenetic inheritance in plants, animals, and even humans. What makes the rice study striking is the clarity of the mechanism and the functional benefit — a heritable trait, induced by environmental stress, that increases fitness and spreads. In other words: this is inheritance, in any evolutionary sense that matters.
So what counts as inheritance?
One answer is purely molecular: only DNA sequence counts, because only sequence is stable, replicable, and “digital.” But this answer is increasingly unsatisfactory. Stability is a matter of degree, not kind. Epigenetic marks can persist across generations. So can maternal effects, microbiomes, learned behaviours, and environmental legacies. If the test of inheritance is whether a trait recurs in offspring and influences evolutionary dynamics, then DNA is not the only medium.
This is the view taken by the Extended Evolutionary Synthesis (EES), which argues for a broader conception of inheritance — one that includes epigenetic, ecological, behavioural, and symbolic systems. From this perspective, inheritance is not just about molecules, but about informational continuity — any process by which prior states constrain or enable future possibilities.
The relational turn takes this one step further: it views inheritance not just as a transmission of pre-formed content, but as a reinstantiation of relational patterns. What is inherited is not a static message, but a set of structured affordances — potentials that can be reactivated, reconfigured, and redeployed in novel contexts.
In this view, the rice plants didn’t pass on a fixed trait. They passed on a conditioned responsiveness, a readiness to activate certain patterns under certain stresses. This responsiveness was made material through epigenetic tags, but its significance lies in the relational history that gave rise to those tags — the plant’s encounter with cold, its selective memory of that encounter, and its conveyance of that memory to the next generation.
This is not Lamarckism in its caricatured form — the idea that any acquired trait can be inherited. Nor is it a rejection of genetic inheritance. Rather, it is a reframing of inheritance as multimodal: a system of layered constraints, some genetic, some epigenetic, some ecological or behavioural, all interacting to shape what becomes possible.
What matters, then, is not whether a trait is written in DNA, but whether it participates in the organism–environment dynamic that makes evolution happen. Inheritance, in this light, is not a chain of discrete handovers. It is a pattern of continuity-in-difference — a means by which the past remains active in the unfolding of the present.
Next, we’ll turn to the heart of the evolutionary process: selection. If variation can be induced, and inheritance is relational, then what exactly is being selected — and by whom?
5 What Counts as Selection? Induction, Participation, and the Environment as Co-Agent
Selection is often framed as the ultimate editor of evolution. Random mutations provide variation; natural selection winnows the results, favouring traits that confer reproductive advantage. On this view, selection is reactive — it operates after the fact, passively eliminating the unfit and letting the fittest survive.
But the rice study complicates this picture. The cold environment doesn’t simply reward plants that happen to survive the stress. It induces heritable change. It participates in shaping the very variation that it will later reward. In this scenario, selection is not an impartial filter. It is an active partner in the generation of traits.
This is not a new idea. Developmental systems theorists and advocates of the Extended Evolutionary Synthesis have long argued that selection is only part of the story — that variation is not always random, and that organisms and environments co-construct one another over time. But what the rice study shows is that this mutual shaping can occur over just a few generations, and that the environment can induce heritable change without altering DNA sequence.
So what counts as selection?
Classically, selection operates on phenotypic variation — differences in traits — and promotes those variants that confer greater reproductive success. But this model presumes a separation: variation is random, selection is external, inheritance is genetic. The rice study dissolves these separations. Variation is not random, but induced. The environment is not external, but entwined. Inheritance is not purely genetic, but epigenetic and relational.
From a relational perspective, selection is not a matter of external pressures acting on isolated traits. It is the co-emergence of trait and context — the mutual attunement of organism and environment over time. Traits are not simply selected; they are made selectable by the histories of interaction that render them meaningful, useful, or viable.
In the rice case, selection is not the cold simply “choosing” those plants that happen to survive. It is the cold interacting with a responsive system — a system capable of reconfiguring itself under stress, of “remembering” that configuration, and of passing it on. This is not natural selection as a sieve. It is selection as a dialogue — a history of adjustments, reciprocal constraints, and shared shaping.
This also suggests a broader account of agency. The environment is not a static backdrop against which evolution plays out. It is an active participant, a co-agent in the evolutionary process. To say that cold “selects” for tolerance is not to anthropomorphise the cold, but to recognise that selection is not one-sided. It emerges from relational entanglement — from the way living systems and their environments co-constitute each other across time.
If variation can be induced, and selection is relational, then evolution is not a one-way process of adaptation to fixed external pressures. It is a process of becoming-with — of reciprocal transformation between organism and world.
In the next post, we will return to the heart of evolutionary theory: the concept of adaptation. What does it mean to adapt in a world where variation is induced, inheritance is multimodal, and selection is mutual?
6 What Counts as Adaptation? The Grammar of Fit in a Co-Created World
Adaptation is the crown jewel of evolutionary explanation. It accounts for the appearance of design without a designer, and for the apparent harmony between organism and environment. Organisms seem fit for their worlds — as if sculpted by the very forces they endure.
But what do we mean by “fit”? In classical Darwinian terms, fitness is about differential reproductive success. Traits that enhance survival and reproduction are selected over time. An adaptation, then, is a trait shaped by this process — a product of natural selection operating on inherited variation.
Yet as we’ve seen, the rice study — and the growing body of work on epigenetics, developmental plasticity, and niche construction — challenges the separability of variation, inheritance, and selection. It invites us to rethink the very notion of adaptation.
Let us pause on the grammar of the word. To “adapt” is to be adapted to, but also to adapt oneself. The first is passive; the second is active. One is done by an external force; the other is done with or through the organism’s own capacities. The rice plants do not merely receive cold tolerance as a selective gift. They actively respond, reorganise, retain, and transmit that capacity — all in relation to the environmental provocation.
This reframes adaptation as not merely a matter of fit, but of fitting-with — a dynamic attunement between organism and world. It is not just that a trait fits an environment; it is that trait and environment are co-shaped in the unfolding of evolutionary time.
The rice plants’ cold tolerance is not simply a pre-existing variant selected from a pool. It is a relational achievement — one that involves perception, response, memory, and reproduction. The trait did not exist before the stress; it emerged with it. In this sense, the adaptation is not a static outcome but a process — an unfolding of potential across instances of interaction.
This view draws attention to the semiotic dimensions of adaptation. Adaptations are not just mechanically useful; they are meaningful within the ecology of interactions in which they arise. The chemical tags that modify the ACT1 gene are not mere switches; they are signals, cues, signs in a system that interprets and responds. The organism is not a passive substrate. It is a participant in the construction of its own capacities to be affected and to affect.
From this perspective, we might say that adaptation is not simply the preservation of form under pressure, but the emergence of form through relation. It is the crystallisation of shared history — of the ways in which organisms and environments have come to matter to one another.
This also has implications for how we understand maladaptation, constraint, and change. If adaptation is not a static match but a living process, then so too is the breakdown of adaptation — not a failure of design, but a shift in relational resonance. What once fit may no longer fit, not because the trait is faulty, but because the context has transformed — or the relationship has frayed.
The rice study teaches us that adaptation is not just an outcome of selection; it is a mode of participation. The plants do not simply endure the cold; they learn with it, remember it, and pass that learning on.
In our final post, we will reflect on what this means for the theory of evolution itself. If variation is induced, inheritance is multimodal, selection is mutual, and adaptation is relational — what kind of theory do we need to account for life as a co-creative process?
7 What Counts as a Theory of Evolution? Towards a Relational Understanding of Life’s Becoming
Evolutionary theory has long been one of the cornerstones of biology, a grand narrative explaining how life diversifies, adapts, and thrives. For much of the twentieth century, the Modern Synthesis—blending Darwin’s natural selection with Mendelian genetics—held sway. It presented evolution as a process driven by random genetic mutations filtered by natural selection, with inheritance confined to DNA sequences.
But the rice study on epigenetic cold tolerance, alongside decades of research into plasticity, developmental systems, and ecological feedback, challenges the simplicity of this framework. It demands a deeper, more relational account of evolution—one that honours the complexity and entanglement of life and environment.
If variation can be induced by the environment, if inheritance operates across multiple channels beyond DNA, if selection is mutual rather than unilateral, and if adaptation is a process of participation rather than mere fit, then our theory of evolution must expand accordingly.
What would such a theory look like?
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Multi-dimensional Inheritance:Inheritance is not limited to DNA sequences. It encompasses epigenetic marks, cellular structures, ecological legacies, cultural knowledge, and behavioural traditions. Each of these forms of inheritance participates in the ongoing construction of organism and environment alike.
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Induced Variation and Developmental Plasticity:Variation is not solely random mutation. Organisms can respond plastically to environmental inputs, producing novel phenotypes that may be stable across generations. Developmental systems shape these responses, enabling organisms to actively participate in their own evolution.
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Relational Selection:Selection is not simply an external filter but a co-creative process. Organisms and environments shape each other reciprocally over time, making traits selectable through their mutual history and context.
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Adaptation as Process:Adaptation is not a static state of “fit” but an ongoing, dynamic process of attunement, interpretation, and transformation. It involves semiotic systems—signalling, memory, and meaning—that mediate organism–environment relations.
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Evolution as Becoming-With:Life does not evolve as isolated entities competing in a fixed arena. It evolves through entangled histories, through becoming-with others—organisms, environments, ecologies, cultures.
This relational view does not reject the power of natural selection or genetics; rather, it situates them within a richer conceptual landscape. It invites us to see evolution not just as change over time but as the unfolding of relational patterns, the weaving of co-constitutive threads that create the fabric of life.
The rice study stands as a landmark, not because it overturns classical theory in one stroke, but because it reveals the multifaceted choreography of evolutionary processes — a dance of genes, molecules, environments, and histories.
Why does this matter?
Embracing relational evolution deepens our understanding of biology and enriches other fields—from ecology to medicine, from philosophy to anthropology. It compels us to rethink agency, causality, and the nature of living systems. It reminds us that life is not a collection of static parts but a dynamic, responsive, and co-creative process.
As we move forward, this perspective opens new avenues for research and reflection—inviting us to ask not only how life evolves, but how we, as part of the living world, evolve with it.